With growing global actions toward sustainability, businesses have to align their course ensuring it as an outcome of their core business strategy. Businesses have to adapt this challenge and create opportunities to integrate sustainability in their goals. This paper provides a brief review of the relevant literature capturing the recent advances in sustainability oriented innovation in business, based on a bibliometric analysis and a systematic review of the highly cited papers indexed by the Web of Knowledge database. The research highlights the links between knowledge, innovation and sustainability in business. The results of this research expand the conceptual background of business sustainability and unveils future research directions in the light of opportunities created by knowledge and innovation.